Authors: Laura Dada, Angel R. Gonzalez, Daniela Urich, Saul Soberanes, Tomas S. Manghi, Sergio E. Chiarella, Navdeep S. Chandel, G. R. Scott Budinger, Gökhan M. Mutlu
DOI: 10.1371/journal.pone.0030448
Abstract Summary
Alcohol worsens acute lung injury by increasing adenosine levels in the lungs, which impairs the body’s ability to clear fluid from air sacs. Mouse studies show alcohol reduces a key sodium pump (Na,K-ATPase) essential for fluid clearance, leading to worse outcomes during lung injury. This adenosine-driven mechanism may explain why alcoholic patients face higher ARDS risk and mortality.
Why Brain? 🧠
Alcohol increases lung adenosine levels, impairing fluid clearance and worsening acute lung injury outcomes. This mechanism explains why alcoholic patients face higher ARDS risk and mortality.
License: CC0 (Public Domain).
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
