Authors: Gómez-Cebrián N, Trull MC, Gras-Colomer E, Edo Solsona MD, Poveda Andrés JL, Puchades-Carrasco L.
DOI: 10.3389/fphar.2025.1702682
Abstract Summary
New research reveals Fabry disease extends beyond enzyme deficiency to include systemic metabolic and gut microbiome disruptions. Multi-omics studies show alterations in mitochondrial function, energy metabolism, and microbial metabolites, explaining persistent symptoms despite current treatments. These findings open pathways for precision diagnostics and novel therapies targeting metabolism and microbiota.
Why Brain? 🧠
Multi-omics studies reveal Fabry disease involves systemic metabolic and gut microbiota disruptions beyond known mechanisms, opening new pathways for biomarkers and targeted therapies.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
