Authors: Poyatos L, Núñez-Montero M, Hladun O, Rosa G, Martín S, Videla S, Martínez-Couselo S, Ventura M, La Maida N, Trana AD, Busardò FP, Torrens M, Pichini S, Pérez-Mañá C, Farré M, Papaseit E.
DOI: 10.3390/ijms27010089
Abstract Summary
Clephedrone (4-CMC), one of the most seized synthetic cathinones, shows a notably delayed onset of stimulant effects compared to methylone, according to a new observational study. Researchers found this pharmacokinetic difference clinically significant, with peak effects and oral fluid concentrations occurring later after clephedrone use—crucial information for understanding abuse patterns and clinical management.
Why Brain? 🧠
Study reveals clephedrone, a common synthetic cathinone, has slower onset than methylone, helping clinicians recognize intoxication patterns and understand abuse potential of emerging drugs.
Study Limitations:
Small sample size of eight volunteers for clephedrone
Non-controlled study design
Observational study design
License: cc by.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
