Authors: Orellana-Paucar AM, Mosquera-Lopez ET, Bustamante-Alvarez NM, Machado-Orellana MG, Vintimilla-Rojas DA, Atiencia-Palacios JD, Espinoza-Fajardo AC.
DOI: 10.3389/fphar.2025.1676685
Abstract Summary
New systematic review reveals phenytoin’s complex food and herb interactions. Key findings: folic acid co-administration appears safe, piperine requires monitoring due to increased absorption, while noni should be avoided as it reduces drug levels to subtherapeutic ranges.
Why Brain? 🧠
Review identifies key food-drug interactions with phenytoin: folic acid appears safe, piperine increases absorption requiring monitoring, and noni juice reduces drug levels and should be avoided.
License: cc by.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
