Authors: Wang J, Li R, Fu X, Huo S, Wang L, Shao F, Gu Y.
DOI: 10.3389/fphar.2025.1686323
Abstract Summary
Researchers developed a novel nanozyme therapy for acute kidney injury (AKI) by combining catalase with manganese sulfide. The CAT@MnS nanozyme targets kidneys, simultaneously neutralizes harmful reactive oxygen species, and reduces inflammation—two key drivers of AKI. Testing in mouse models showed significant kidney protection and damage reduction, offering a promising new treatment approach for this serious condition lacking effective therapies.
Why Brain? đź§
Novel nanozyme combining catalase with manganese sulfide effectively targets kidneys to reduce oxidative stress and inflammation in acute kidney injury models, offering a promising new therapeutic approach.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
