Authors: Li-Ming Wu, Zhe Yang, Lin Zhou, Feng Zhang, Hai-Yang Xie, Xiao-Wen Feng, Jian Wu, Shu-Sen Zheng DOI: 10.1371/journal.pone.0014460 Abstract Summary HDAC3, a histone-modifying enzyme, emerges as a key player in hepatocellular carcinoma progression....
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Authors: Grégory Lacraz, Marie-Hélène Giroix, Nadim Kassis, Josiane Coulaud, Anne Galinier, Christophe Noll, Mélanie Cornut, Fabien Schmidlin, Jean-Louis Paul, Nathalie Janel, Jean-Claude Irminger, Micheline Kergoat, Bernard Portha, Marc Y. Donath, Jan A. Ehses, Françoise...
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Authors: Rosamond Lougheed, John Turnbull DOI: 10.1371/journal.pone.0023141 Abstract Summary Methylene blue, a well-established drug with promising theoretical benefits for ALS, showed limited efficacy in mice carrying the SOD1 G93A mutation. While treated mice spent...
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Authors: Tot Bui, Jeff Stevenson, John Hoekman, Shanrong Zhang, Kenneth Maravilla, Rodney J. Y. Ho DOI: 10.1371/journal.pone.0013082 Abstract Summary Researchers developed gadolinium-lipid nanoparticles (Gd-LNP) that achieve 33-fold higher MRI contrast sensitivity than current agents,...
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Authors: Linley E. Watson, Shu-ru Kuo, Khurshed Katki, Tongyun Dang, Seong Kyu Park, David E. Dostal, Wei-Jen Tang, Stephen H. Leppla, Arthur E. Frankel DOI: 10.1371/journal.pone.0000466 Abstract Summary Anthrax toxins cause deadly hypotensive shock...
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