Uremic Toxins Induce Kidney Fibrosis by Activating Intrarenal Renin–Angiotensin–Aldosterone System Associated Epithelial-to-Mesenchymal Transition
Authors: Chiao-Yin Sun, Shih-Chung Chang, Mai-Szu Wu DOI: 10.1371/journal.pone.0034026 Abstract Summary Uremic toxins indoxyl sulfate and p-cresol sulfate drive chronic kidney disease progression by activating the renal renin-angiotensin system and TGF-β pathway, triggering epithelial-to-mesenchymal...
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