Authors: Chiao-Yin Sun, Shih-Chung Chang, Mai-Szu Wu DOI: 10.1371/journal.pone.0034026 Abstract Summary Uremic toxins indoxyl sulfate and p-cresol sulfate drive chronic kidney disease progression by activating the renal renin-angiotensin system and TGF-β pathway, triggering epithelial-to-mesenchymal...
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Authors: Hong-Yuan Chu, Qinhua Gu, Guo-Zhang Jin, Guo-Yuan Hu, Xuechu Zhen DOI: 10.1371/journal.pone.0013118 Abstract Summary SKF83959, a drug used for Parkinson's disease, protects neurons through a newly discovered mechanism. Researchers found it activates HCN...
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Authors: Aws Alherbish, Theresa L. Charrois, Margaret L. Ackman, Ross T. Tsuyuki, Justin A. Ezekowitz DOI: 10.1371/journal.pone.0019623 Abstract Summary Natural health products (NHPs) are widely used by cardiovascular patients (78%), yet poorly documented by...
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Authors: Mario Bonomini, Annalisa Giardinelli, Caterina Morabito, Sara Di Silvestre, Moreno Di Cesare, Natalia Di Pietro, Vittorio Sirolli, Gloria Formoso, Luigi Amoroso, Maria Addolorata Mariggiò, Assunta Pandolfi DOI: 10.1371/journal.pone.0030682 Abstract Summary Calcimimetics like R-568,...
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Authors: Stefan Balabanov, Artur Gontarewicz, Gunhild Keller, Laura Raddrizzani, Melanie Braig, Roberta Bosotti, Jürgen Moll, Edgar Jost, Christine Barett, Imke Rohe, Carsten Bokemeyer, Tessa L. Holyoake, Tim H. Brümmendorf DOI: 10.1371/journal.pone.0019164 Abstract Summary Danusertib,...
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