Authors: Jingwei Zhang, Fang Zhou, Fang Niu, Meng Lu, Xiaolan Wu, Jianguo Sun, Guangji Wang DOI: 10.1371/journal.pone.0035768 Abstract Summary Researchers discovered that ginsenoside Rh2 stereoisomers regulate P-glycoprotein differently based on their 3D structure. The...
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Authors: Yu-Hao Zhou, Xiu-Qiang Ma, Cheng Wu, Jian Lu, Shan-Shan Zhang, Jia Guo, Shun-Quan Wu, Xiao-Fei Ye, Jin-Fang Xu, Jia He DOI: 10.1371/journal.pone.0039062 Abstract Summary This meta-analysis of anti-obesity drugs found that orlistat improved...
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Authors: Ulrike Böer, Tahseen Alejel, Stephan Beimesche, Irmgard Cierny, Doris Krause, Willhart Knepel, Gabriele Flügge DOI: 10.1371/journal.pone.0000431 Abstract Summary Researchers created transgenic mice to track CREB transcription factor activity in the brain. Chronic social...
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Authors: Lesley A. Rakowski, Erica A. Lehotzky, Mark Y. Chiang DOI: 10.1371/journal.pone.0016761 Abstract Summary Researchers developed a mouse model showing that TLX1, a transcription factor dysregulated in 30-40% of T-cell leukemia cases, drives cancer...
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Authors: Jan-Rung Mo, Anjili Mathur, Minilik Angagaw, Shuxia Zhao, Yuxun Wang, Diana Gargano, Alessandra DiBacco, Eric S. Bachman DOI: 10.1371/journal.pone.0007286 Abstract Summary Researchers found that the spleen plays a crucial role in polycythemia vera...
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