Authors: Madalina Rujoi, Nina H. Pipalia, Frederick R. Maxfield DOI: 10.1371/journal.pone.0012788 Abstract Summary Researchers identified compounds that reduce cholesterol buildup in Niemann-Pick type C disease, a rare genetic disorder affecting lipid storage. The chemicals...
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Authors: Li-sheng Zheng, Fang Wang, Yu-hong Li, Xu Zhang, Li-ming Chen, Yong-ju Liang, Chun-ling Dai, Yan-yan Yan, Li-yang Tao, Yan-jun Mi, An-kui Yang, Kenneth Kin Wah To, Li-wu Fu DOI: 10.1371/journal.pone.0005172 Abstract Summary Vandetanib,...
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Authors: Frank Ludewig, Anke Hüser, Hillel Fromm, Linda Beauclair, Nicolas Bouché DOI: 10.1371/journal.pone.0003383 Abstract Summary Researchers found that blocking a specific step in plant metabolism causes toxic buildup rather than nutrient deficiency. When the...
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Authors: Duong P. Huynh, Marwan Maalouf, Alcino J. Silva, Felix E. Schweizer, Stefan M. Pulst DOI: 10.1371/journal.pone.0006235 Abstract Summary Ataxin-2 knockout mice show impaired fear responses and motor hyperactivity while maintaining normal memory function....
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Authors: Michaela Lucas, Axel Ulsenheimer, Katja Pfafferot, Malte H.J. Heeg, Silvana Gaudieri, Norbert Grüner, Andri Rauch, J. Tilman Gerlach, Maria-Christina Jung, Reinhart Zachoval, Gerd R. Pape, Winfried Schraut, Teresa Santantonio, Hans Nitschko, Martin Obermeier,...
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