Authors: Lin H, Yang C, Zhu J, Yang C, Xu Z, Wu Z, Wang X, Wang W.
DOI: 10.3389/fonc.2025.1651271
Abstract Summary
A 27-year-old man developed three separate bone tumors over 10 yearsโa rare case of metachronous multicentric giant cell tumor. Lesions appeared sequentially in his right femur and tibia. Treatment combined mega-prosthesis revision with denosumab therapy and curettage, highlighting the need for long-term monitoring and multimodal approaches in managing this exceptionally rare condition.
Why Brain? ๐ง
Rare case shows sequential bone tumors over 10 years successfully managed with denosumab therapy and prosthesis revision, highlighting effective treatment strategy for multicentric giant cell tumors.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
