Authors: Quijano-Lievano ML, Ramirez O, Chen Y, Robles-Murguia M, Devidas M, Muñiz-Talavera H, Cárdenas-Aguirre A, Portilla C, Castrillon D, Rendon D, De Paula ARPA, Diaz-Coronado R, Sánchez-Martín M, Torres S, Soto Chávez V, Agulnik A.
DOI: 10.3389/fonc.2025.1712611
Abstract Summary
Implementing a Pediatric Early Warning Score (PEWS) system in stem cell transplant units across South America and Europe led to earlier detection of clinical deterioration in children. After PEWS implementation, patients transferred to ICU had fewer failing organ systems and lower illness severity scores, suggesting critical conditions were caught sooner. The study analyzed 221 deterioration events in 146 patients, showing promising trends toward improved outcomes for this vulnerable population.
Why Brain? 🧠
Early warning system implementation in pediatric stem cell transplant units reduced illness severity at ICU transfer and respiratory distress events, supporting global use in pediatric oncology care.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.



