Authors: Lin YC, Lee JC, Wen CY, Chiu WY.
DOI: 10.3389/fonc.2025.1720028
Abstract Summary
Rare case report: An 87-year-old patient experienced two distinct episodes of hypercalcemia—first from an ectopic parathyroid adenoma in the mediastinum, then from a pelvic GIST two years later. Advanced imaging (4D-CT, FCH-PET/CT) proved valuable for localizing ectopic parathyroid lesions when standard scans fail. GIST-related hypercalcemia, extremely uncommon, likely involves PTHrP or 1-alpha-hydroxylase expression.
Why Brain? đź§
Rare case shows two distinct causes of hypercalcemia: ectopic parathyroid adenoma and gastrointestinal stromal tumor. Advanced imaging like 4D-CT and FCH-PET/CT aids diagnosis when standard tests fail.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
