Monday, February 9, 2026

Biomarkers in gastroesophageal cancer 2025: an updated consensus statement by the Spanish Society of Medical Oncology (SEOM) and the Spanish Society of Pathology (SEAP).

Authors: Alsina Maqueda M, Teijo Quintáns A, Cuatrecasas M, Fernández Aceñero MJ, Fernández Montes A, Gómez Martín C, Jiménez Fonseca P, Martínez Ciarpaglini C, Rivera Herrero F, Iglesias Coma M.

DOI: 10.1007/s12094-025-03865-6

Abstract Summary

New Spanish consensus guidelines identify four essential biomarkers (HER2, dMMR/MSI, PD-L1, Claudin18.2) for personalized gastroesophageal cancer treatment. With expanding therapeutic options beyond trastuzumab, immunohistochemistry-based biomarker testing is now crucial for optimizing targeted therapies in advanced disease.

Why Brain? 🧠

Spanish experts establish consensus on key biomarkers (HER2, dMMR/MSI, PD-L1, Claudin18.2) for personalized treatment of gastroesophageal cancers, optimizing targeted therapy selection in clinical practice.

License: cc by.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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