Authors: Robert M. Kwee, Paul A. M. Hofman, Ed H. B. M. Gronenschild, Robert J. van Oostenbrugge, Werner H. Mess, Johannes W. M. ter. Berg, Cees L. Franke, Arthur G. G. C. Korten, Bé J. Meems, Jos M. A. van Engelshoven, Joachim E. Wildberger, M. Eline Kooi
DOI: 10.1371/journal.pone.0017070
Abstract Summary
Study of 50 TIA/stroke patients reveals carotid plaque size correlates with baseline brain white matter lesions, but plaque vulnerability features—like lipid cores, fibrous cap status, or hemorrhage—don’t predict new lesion development over one year. Findings suggest plaque burden reflects overall vascular disease rather than directly causing white matter damage.
Why Brain? 🧠
Carotid plaque size correlates with brain white matter lesions, but plaque instability features don’t predict new lesion development, suggesting alternative mechanisms drive brain damage in stroke patients.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
