Sunday, January 18, 2026

The Directed Differentiation of Human iPS Cells into Kidney Podocytes

Authors: Bi Song, Alexandra M. Smink, Christina V. Jones, Judy M. Callaghan, Stephen D. Firth, Claude A. Bernard, Andrew L. Laslett, Peter G. Kerr, Sharon D. Ricardo

DOI: 10.1371/journal.pone.0046453

Abstract Summary

Researchers successfully created kidney podocytes from induced pluripotent stem cells for the first time. These lab-grown cells displayed key podocyte characteristics, responded to hormones, and integrated into developing kidney tissue. This breakthrough offers new possibilities for testing treatments, studying kidney disease mechanisms, and advancing regenerative medicine for chronic kidney disease.

Why Brain? 🧠

Scientists successfully created kidney podocytes from stem cells for the first time. These lab-grown cells could help test new treatments for chronic kidney disease and advance regenerative medicine.

License: CC BY.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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