Authors: Fabian Zimmer, Frank G. Zöllner, Simone Hoeger, Sarah Klotz, Charalambos Tsagogiorgas, Bernhard K. Krämer, Lothar R. Schad
DOI: 10.1371/journal.pone.0053849
Abstract Summary
Researchers successfully used arterial spin labeling (ASL), a contrast-free MRI technique, to measure kidney perfusion in rats with acute kidney injury. Both ASL and traditional contrast-enhanced MRI detected significantly reduced blood flow in damaged kidneys (P<0.01), though ASL yielded lower absolute values. This validates ASL as a promising alternative for assessing renal perfusion without contrast agents.
Why Brain? 🧠
ASL and DCE-MRI both effectively detect reduced kidney perfusion in acute kidney injury at 3T MRI, with ASL offering a contrast-free alternative despite differences in absolute values between methods.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
