Authors: Danis J, Kelemen E, Balogh F, Szabó K, Fodor GH, Ádám É, Széll M.
DOI: 10.1371/journal.pone.0336901
Abstract Summary
New research reveals that self-derived DNA and RNA trigger potent inflammatory responses in skin cells by dramatically increasing chemokine production. These nucleic acids boost key inflammatory proteins like CCL2, CXCL10, and CX3CL1 through NF-κB activation, potentially driving chronic skin diseases including psoriasis and atopic dermatitis.
Why Brain? 🧠
Self-derived nucleic acids trigger inflammatory chemokine production in skin cells via NF-κB, offering new insights into chronic skin diseases like psoriasis and atopic dermatitis pathogenesis.
License: cc by.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
