Authors: Tsolakidou PJ.
DOI: 10.3389/fmicb.2025.1725247
Abstract Summary
CRISPR technology shows promise against drug-resistant superbugs. Scientists are developing Cas9, Cas13, and Cas3 systems to selectively eliminate carbapenem-resistance genes from dangerous bacteria. Conjugative plasmids can deliver these gene editors between bacteria without lab manipulation, while phage-based therapies have reached early clinical trials. Key challenges include delivery efficiency and ecological safety, but novel platforms like nanoparticles and engineered vesicles may overcome current limitations.
Why Brain? ðŸ§
CRISPR gene-editing tools can selectively eliminate carbapenem-resistance genes in deadly bacteria, offering a precise alternative to antibiotics as some approaches enter early human trials.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
