Authors: Dinneen E, Dasgupta P, Sharma A, Nisaa K, Silva-García CG.
DOI: 10.1093/g3journal/jkaf220
Abstract Summary
Researchers developed SKI PLACE, a streamlined gene insertion system for C. elegans that uses just one plasmid to target any chromosome. This CRISPR/Cas9-based tool simplifies transgene insertion with standardized harbor sites, flexible cloning options, and easy tracking—making genetic studies more efficient.
Why Brain? 🧠
New CRISPR tool enables precise single-copy gene insertion at any chromosome location in C. elegans using one plasmid, streamlining genetic studies and accelerating research on gene function.
License: cc by.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
