Sunday, January 18, 2026

Towards Rational Use of Antibiotics for Suspected Secondary Infections in Buruli Ulcer Patients

Authors: Yves T. Barogui, Sandor Klis, Honoré Sourou Bankolé, Ghislain E. Sopoh, Solomon Mamo, Lamine Baba-Moussa, Willem L. Manson, Roch Christian Johnson, Tjip S. van der Werf, Ymkje Stienstra

DOI: 10.1371/journal.pntd.0002010

Abstract Summary

Study reveals 78% of hospitalized Buruli ulcer patients in Ghana and Bénin received additional antibiotics beyond standard treatment, mostly as prophylaxis rather than for actual infections. Antibiotic use varied widely and often extended unnecessarily post-surgery. Concerningly, 38% of S. aureus isolates were MRSA. Researchers propose new guidelines to rationalize antibiotic use, potentially reducing costs, toxicity, and antimicrobial resistance in BU management.

Why Brain? 🧠

Study reveals 78% of hospitalized Buruli ulcer patients receive unnecessary prophylactic antibiotics, with high MRSA rates detected. New guidelines could reduce costs, toxicity, and antimicrobial resistance.

License: CC BY.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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