Authors: Andrew C. Kotze, Steven R. Kopp
DOI: 10.1371/journal.pntd.0000297
Abstract Summary
Monitoring drug resistance in human parasitic worms faces a critical challenge: surviving worms may boost egg production after treatment, masking true drug efficacy. This density-dependent response means standard fecal egg count tests could underestimate how well drugs work, complicating resistance detection efforts. Researchers suggest excluding heavily infected cases from testing and developing new molecular methods.
Why Brain? đź§
Drug resistance testing in hookworms may be unreliable because surviving worms increase egg production after treatment, masking true drug efficacy and necessitating better monitoring methods.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
