Authors: Francine Matthys, Leen Rigouts, Vinciane Sizaire, Natalia Vezhnina, Maryvonne Lecoq, Vera Golubeva, Françoise Portaels, Patrick Van der Stuyft, Michael Kimerling
DOI: 10.1371/journal.pone.0007954
Abstract Summary
In prisons with high drug-resistant TB, WHO’s standard retreatment regimen showed concerning results: only 74% of patients cleared infection, while 18% failed treatment. Most failures stemmed from inadequate drug regimens for resistant strains, though mixed infections and reinfection also played roles. Drug resistance worsened in 3.4% of cases, highlighting the need for better treatment strategies in high-resistance settings.
Why Brain? 🧠
Study shows WHO standard TB retreatment fails in 18% of prison cases with high drug resistance, with treatment amplifying resistance in 3.4% and reinfection contributing to failures.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
