Authors: Bingqing Zhu, Di Xiao, Huifang Zhang, Yongchan Zhang, Yuan Gao, Li Xu, Jing Lv, Yingtong Wang, Jianzhong Zhang, Zhujun Shao
DOI: 10.1371/journal.pone.0056139
Abstract Summary
MALDI-TOF mass spectrometry proves highly effective for distinguishing pathogenic Nontypable Haemophilus influenzae from H. haemolyticus—a critical clinical challenge. While standard databases identified only 77% of NTHi strains, an enhanced database with Chinese strains achieved 100% accuracy for both species, outperforming traditional methods in speed and throughput.
Why Brain? 🧠
MALDI-TOF MS accurately distinguishes pathogenic nontypable H. influenzae from H. haemolyticus when using an enhanced database with Chinese strains, offering faster, more reliable identification than existing methods.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
