Authors: Sophie A. Valkenburg, Vanessa Venturi, Thurston H. Y. Dang, Nicola L. Bird, Peter C. Doherty, Stephen J. Turner, Miles P. Davenport, Katherine Kedzierska
DOI: 10.1371/journal.ppat.1002544
Abstract Summary
Early flu vaccination may provide lifelong protection against age-related immune decline. Research shows mice vaccinated at 6 weeks maintained strong T-cell responses over 20 months later, while late vaccination reduced immune diversity. Early priming preserves optimal CD8+ T-cell memory, suggesting childhood vaccines could offer broader, longer-lasting immunity against influenza throughout aging.
Why Brain? đź§
Early influenza vaccination preserves immune function in elderly by maintaining CD8+ T cell diversity and preventing age-related immune decline, supporting youth vaccination strategies.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
