Authors: Chih-Hsi Kuo, Hao-Cheng Chen, Fu-Tsai Chung, Yu-Lun Lo, Kang-Yun Lee, Chih-Wei Wang, Wen-Han Kuo, Tzu-Chen Yen, Han-Pin Kuo
DOI: 10.1371/journal.pone.0016877
Abstract Summary
In TB-endemic regions, PET scans often mislead lung cancer staging due to false positives from TB-related inflammation. This study of 43 patients found EBUS-TBNA achieved 91% diagnostic accuracy versus just 47% for PET in non-enlarged lymph nodes. PET’s poor specificity (19%) led to negative diagnostic impact in 46% of cases, especially in patients with prior TB. EBUS-TBNA offers superior nodal staging through direct tissue sampling.
Why Brain? ðŸ§
EBUS-TBNA outperforms PET scanning for lymph node staging in lung cancer patients with non-enlarged nodes in TB-endemic regions, offering superior accuracy (91% vs 47%) and avoiding false positives from TB.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
