Authors: Ramon A. Juste, Natalia Elguezabal, Joseba M. Garrido, Andres Pavon, Maria V. Geijo, Iker Sevilla, Jose-Luis Cabriada, Angel Tejada, Francisco García-Campos, Roberto Casado, Itziar Ochotorena, Ander Izeta, Robert J. Greenstein
DOI: 10.1371/journal.pone.0002537
Abstract Summary
Researchers found MAP bacteria DNA in 47% of healthy individuals but only 16% of IBD patients. This surprising difference appears linked to IBD medications—drugs like methotrexate and 6-MP, which have anti-MAP properties, were associated with complete clearance of MAP DNA from blood. The findings suggest common IBD treatments may inadvertently act as antibiotics against this widespread pathogen.
Why Brain? 🧠
Study finds 47% of healthy people carry M. paratuberculosis DNA in blood versus only 16% of IBD patients, suggesting common IBD medications may act as antibiotics clearing this cattle pathogen from humans.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
