Monday, March 2, 2026

Mechanistic roles and therapeutic potential of bacteriophages in inflammatory gastrointestinal diseases.

Authors: Ding B, Fan M, Shi YP, Chen X, Duan Y.

DOI: 10.20517/mrr.2025.62

Abstract Summary

The gut virome, especially bacteriophages, plays a crucial role in gastrointestinal inflammatory diseases beyond bacterial imbalances. These viruses influence microbial stability and immune responses in conditions like IBD, liver diseases, and pancreatitis. With rising antibiotic resistance, phage therapy is gaining renewed attention as a promising treatment approach, supported by animal studies and early clinical trials.

Why Brain? ๐Ÿง 

Phages shape gut immunity and microbiome balance in IBD, hepatitis, and pancreatitis; this review highlights phage therapy’s therapeutic promise and translation challenges.

Study Limitations:

Study limitations were not specified in the abstract.

License: cc by.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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