Monday, December 1, 2025

Lactobacillus casei Abundance Is Associated with Profound Shifts in the Infant Gut Microbiome

Authors: Michael J. Cox, Yvonne J. Huang, Kei E. Fujimura, Jane T. Liu, Michelle McKean, Homer A. Boushey, Mark R. Segal, Eoin L. Brodie, Michael D. Cabana, Susan V. Lynch

DOI: 10.1371/journal.pone.0008745

Abstract Summary

Probiotic supplementation with Lactobacillus rhamnosus (LGG) in 6-month-old infants promotes a more balanced and stable gut microbiome. High-density microarray analysis revealed that LGG encourages growth of beneficial bacterial species while creating a more evenly distributed microbial community—characteristics linked to better resistance against pathogens and disease. This stabilizing effect may explain how LGG protects against childhood allergies and asthma.

Why Brain? 🧠

Probiotic supplementation with Lactobacillus casei in infants promotes a more stable, diverse gut microbiome that may protect against allergies and asthma by preventing harmful bacterial overgrowth.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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