Authors: Irene Esposito, Diana Born, Frank Bergmann, Thomas Longerich, Thilo Welsch, Nathalia A. Giese, Markus W. Büchler, Jörg Kleeff, Helmut Friess, Peter Schirmacher
DOI: 10.1371/journal.pone.0002539
Abstract Summary
Autoimmune pancreatocholangitis (AIPC) primarily affects the pancreatic head, with biliary tract involvement in 64% of cases. A European study of 33 patients revealed distinctive features: significantly elevated T-lymphocytes, macrophages, and plasma cells compared to chronic pancreatitis, plus unique immunological markers (IgG4, CXCR5, CXCL13) that aid diagnosis and distinguish AIPC from similar conditions.
Why Brain? 🧠
Study identifies distinct immunological markers (IgG4, CXCR5, CXCL13) that differentiate autoimmune pancreatocholangitis from similar conditions, improving diagnostic accuracy for this emerging disease.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
