Thursday, February 19, 2026

Thyroid function and liver fibrosis: FT3 levels are inversely and independently correlated with enhanced liver fibrosis score in solid organ transplant patients with dysglycemia.

Authors: Leanza C, Giusti MA, Miceli V, Zito G, Tinnirello R, Iannolo G, Galante A, Emanuele F, Amato M, Lo Iacono G, Lo Re V, Gruttadauria S, Calogero AE, Pinzani M, Mattina A.

DOI: 10.3389/fimmu.2025.1726617

Abstract Summary

Lower thyroid hormone levels (FT3) were independently linked to higher liver fibrosis scores in organ transplant recipients with diabetes or prediabetes. This study of 71 patients suggests thyroid function may influence liver scarring in metabolically vulnerable transplant patients, opening new avenues for monitoring and potential intervention strategies.

Why Brain? ๐Ÿง 

Lower FT3 thyroid hormone levels independently correlate with increased liver fibrosis in transplant patients with diabetes, suggesting thyroid function may influence liver disease progression.

Study Limitations:

Small sample size of seventy-one participants
Cross-sectional design preventing determination of causal directionality

License: cc by.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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