Authors: Dobre MZ, Virgolici B, Dunca-Stefan DCA, Doicin IC, Stanescu-Spinu II.
DOI: 10.3390/ijms27010060
Abstract Summary
Insulin resistance and chronic inflammation drive metabolic diseases like type 2 diabetes and liver disease. Myokinesโsignaling molecules from skeletal muscleโplay a crucial role: exercise-induced myokines improve insulin sensitivity and reduce inflammation, while others like myostatin worsen metabolism. This review highlights how muscle communicates with liver, pancreas, and thyroid, linking muscle loss to metabolic dysfunction.
Why Brain? ๐ง
Myokines from skeletal muscle regulate insulin resistance and inflammation, linking muscle health to diabetes, obesity, and thyroid disorders. Preserving muscle mass through exercise is key to metabolic health.
Study Limitations:
Study limitations were not specified in the abstract.
License: cc by.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
