Authors: Yang Y, Shahinozzaman M, Shin H, Bupp S, Sourbier C.
DOI: 10.3389/fendo.2025.1601119
Abstract Summary
From animal extracts to cutting-edge biosimilars, insulin has evolved dramatically since the 1920s. Today, over 50 FDA-approved insulin products offer tailored diabetes treatment through recombinant DNA technology and innovative formulations. Recent advances include ultra-rapid formulations and combination therapies with diverse time-action profiles, making diabetes management safer, more effective, and personalized.
Why Brain? ðŸ§
Review traces insulin’s evolution from animal sources to modern analogs, explaining how structural and formulation changes created diverse products with varied action profiles, improving diabetes management.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
