Authors: Giovanni Cizza, Donna S. Ronsaville, Hayley Kleitz, Farideh Eskandari, Sejal Mistry, Sara Torvik, Nina Sonbolian, James C. Reynolds, Marc R. Blackman, Philip W. Gold, Pedro E. Martinez
DOI: 10.1371/journal.pone.0028912
Abstract Summary
Premenopausal women with major depression show distinct metabolic and bone health profiles depending on their depression subtype. Those with atypical or undifferentiated features had higher BMI and abdominal fat, while undifferentiated depression linked to elevated lipids, glucose, and lower bone density. Each subtype showed unique hormonal patterns, suggesting depression subtypes may carry different long-term health risks.
Why Brain? ðŸ§
Different depression subtypes in premenopausal women show distinct metabolic and hormonal profiles, potentially explaining varying risks for cardiovascular disease and osteoporosis in depressed patients.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
