Pharmacology
Sphingosine Kinase-1 (SphK-1) Regulates Mycobacterium smegmatis Infection in Macrophages
Authors: Hridayesh Prakash, Anja Lüth, Natalia Grinkina, Daniela Holzer, Raj Wadgaonkar, Alexis Perez Gonzalez, Elsa Anes, Burkhard Kleuser DOI: 10.1371/journal.pone.0010657...
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Cardioprotective Effect of Paeonol and Danshensu Combination on Isoproterenol-Induced Myocardial Injury in Rats
Authors: Hua Li, Yan-Hua Xie, Qian Yang, Si-Wang Wang, Bang-Le Zhang, Jian-Bo Wang, Wei Cao, Lin-Lin Bi, Ji-Yuan Sun, Shan...
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Vandetanib (Zactima, ZD6474) Antagonizes ABCC1- and ABCG2-Mediated Multidrug Resistance by Inhibition of Their Transport Function
Authors: Li-sheng Zheng, Fang Wang, Yu-hong Li, Xu Zhang, Li-ming Chen, Yong-ju Liang, Chun-ling Dai, Yan-yan Yan, Li-yang Tao, Yan-jun...
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nAChRs Mediate Human Embryonic Stem Cell-Derived Endothelial Cells: Proliferation, Apoptosis, and Angiogenesis
Authors: Jin Yu, Ngan F. Huang, Kitchener D. Wilson, Jeffrey B. Velotta, Mei Huang, Zongjin Li, Andrew Lee, Robert C....
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Quantitative Whole Body Biodistribution of Fluorescent-Labeled Agents by Non-Invasive Tomographic Imaging
Authors: Kristine O. Vasquez, Chelsea Casavant, Jeffrey D. Peterson DOI: 10.1371/journal.pone.0020594 Abstract Summary Fluorescence molecular tomography (FMT) enables non-invasive, real-time...
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A Taxpayer-Funded Clinical Trials Registry and Results Database
Authors: Erick H Turner DOI: 10.1371/journal.pmed.0010060 Abstract Summary A former FDA clinical reviewer of psychotropic drugs argues that the necessary...
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Statin Induced Myopathy and Myalgia: Time Trend Analysis and Comparison of Risk Associated with Statin Class from 1991–2006
Authors: Mariam Molokhia, Paul McKeigue, Vasa Curcin, Azeem Majeed DOI: 10.1371/journal.pone.0002522 Abstract Summary Statins significantly increase myopathy risk, with rates...
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Herbal Medicines for Parkinson’s Disease: A Systematic Review of Randomized Controlled Trials
Authors: Tae-Hun Kim, Ki-Ho Cho, Woo-Sang Jung, Myeong Soo Lee DOI: 10.1371/journal.pone.0035695 Abstract Summary A systematic review of 64 studies...
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Patient Organizations’ Funding from Pharmaceutical Companies: Is Disclosure Clear, Complete and Accessible to the Public? An Italian Survey
Authors: Cinzia Colombo, Paola Mosconi, Walter Villani, Silvio Garattini DOI: 10.1371/journal.pone.0034974 Abstract Summary Italian patient advocacy groups show poor transparency...
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Chronic Obstructive Pulmonary Disease: A Growing but Neglected Global Epidemic
Authors: Peter J Barnes DOI: 10.1371/journal.pmed.0040112 Abstract Summary COPD represents a growing global health crisis that remains severely underrecognized. Despite...
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