Neurological Disorders
Dissociated Fear and Spatial Learning in Mice with Deficiency of Ataxin-2
Authors: Duong P. Huynh, Marwan Maalouf, Alcino J. Silva, Felix E. Schweizer, Stefan M. Pulst DOI: 10.1371/journal.pone.0006235 Abstract Summary Ataxin-2...
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MRI Pattern Recognition in Multiple Sclerosis Normal-Appearing Brain Areas
Authors: Martin Weygandt, Kerstin Hackmack, Caspar Pfüller, Judith Bellmann–Strobl, Friedemann Paul, Frauke Zipp, John–Dylan Haynes DOI: 10.1371/journal.pone.0021138 Abstract Summary Machine...
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Evidence for Gender-Specific Transcriptional Profiles of Nigral Dopamine Neurons in Parkinson Disease
Authors: Filip Simunovic, Ming Yi, Yulei Wang, Robert Stephens, Kai C. Sonntag DOI: 10.1371/journal.pone.0008856 Abstract Summary Gene expression analysis of...
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Different Susceptibility to the Parkinson’s Toxin MPTP in Mice Lacking the Redox Master Regulator Nrf2 or Its Target Gene Heme Oxygenase-1
Authors: Nadia G. Innamorato, Agnieszka Jazwa, Ana I. Rojo, Concepción García, Javier Fernández-Ruiz, Anna Grochot–Przeczek, Anna Stachurska, Alicja Jozkowicz, Jozef...
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A Putative Alzheimer’s Disease Risk Allele in PCK1 Influences Brain Atrophy in Multiple Sclerosis
Authors: Zongqi Xia, Lori B. Chibnik, Bonnie I. Glanz, Maria Liguori, Joshua M. Shulman, Dong Tran, Samia J. Khoury, Tanuja...
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Calcineurin Inhibition at the Clinical Phase of Prion Disease Reduces Neurodegeneration, Improves Behavioral Alterations and Increases Animal Survival
Authors: Abhisek Mukherjee, Diego Morales-Scheihing, Dennisse Gonzalez-Romero, Kristi Green, Giulio Taglialatela, Claudio Soto DOI: 10.1371/journal.ppat.1001138 Abstract Summary Researchers found that...
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Alzheimer’s Disease Amyloid-β Links Lens and Brain Pathology in Down Syndrome
Authors: Juliet A. Moncaster, Roberto Pineda, Robert D. Moir, Suqian Lu, Mark A. Burton, Joy G. Ghosh, Maria Ericsson, Stephanie...
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Switching Multiple Sclerosis Patients with Breakthrough Disease to Second-Line Therapy
Authors: Tamara Castillo-Trivino, Ellen M. Mowry, Alberto Gajofatto, Dorothee Chabas, Elizabeth Crabtree-Hartman, Bruce A. Cree, Douglas S. Goodin, Ari J....
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A 50-Year-Old Man with Deteriorating Cognitive Function and Impaired Movement
Authors: Andrew J Larner DOI: 10.1371/journal.pmed.1000019 Abstract Summary A case study explores the diagnostic workup and treatment approach for a...
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Evidence of Key Tinnitus-Related Brain Regions Documented by a Unique Combination of Manganese-Enhanced MRI and Acoustic Startle Reflex Testing
Authors: Avril Genene Holt, David Bissig, Najab Mirza, Gary Rajah, Bruce Berkowitz DOI: 10.1371/journal.pone.0014260 Abstract Summary Researchers combined behavioral testing...
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