Neurological Disorders
Chronic Cyclodextrin Treatment of Murine Niemann-Pick C Disease Ameliorates Neuronal Cholesterol and Glycosphingolipid Storage and Disease Progression
Authors: Cristin D. Davidson, Nafeeza F. Ali, Matthew C. Micsenyi, Gloria Stephney, Sophie Renault, Kostantin Dobrenis, Daniel S. Ory, Marie...
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Risks for Central Nervous System Diseases among Mobile Phone Subscribers: A Danish Retrospective Cohort Study
Authors: Joachim Schüz, Gunhild Waldemar, Jørgen H. Olsen, Christoffer Johansen DOI: 10.1371/journal.pone.0004389 Abstract Summary A Danish study of 420,095 early...
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Adipokine Hormones and Hand Osteoarthritis: Radiographic Severity and Pain
Authors: Mei Massengale, Bing Lu, John J. Pan, Jeffrey N. Katz, Daniel H. Solomon DOI: 10.1371/journal.pone.0047860 Abstract Summary This pilot...
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Beyond PrP res Type 1/Type 2 Dichotomy in Creutzfeldt-Jakob Disease
Authors: Emmanuelle Uro-Coste, Hervé Cassard, Stéphanie Simon, Séverine Lugan, Jean-Marc Bilheude, Armand Perret-Liaudet, James W. Ironside, Stéphane Haik, Christelle Basset-Leobon,...
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Reduced NAA-Levels in the NAWM of Patients with MS Is a Feature of Progression. A Study with Quantitative Magnetic Resonance Spectroscopy at 3 Tesla
Authors: Fahmy Aboul-Enein, Martin Krššák, Romana Höftberger, Daniela Prayer, Wolfgang Kristoferitsch DOI: 10.1371/journal.pone.0011625 Abstract Summary MRI spectroscopy reveals that axonal...
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Delayed Postconditioning Protects against Focal Ischemic Brain Injury in Rats
Authors: Chuancheng Ren, Xuwen Gao, Gang Niu, Zhimin Yan, Xiaoyuan Chen, Heng Zhao DOI: 10.1371/journal.pone.0003851 Abstract Summary Researchers discovered that...
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Nucleoside Analogue Reverse Transcriptase Inhibitors Differentially Inhibit Human LINE-1 Retrotransposition
Authors: R. Brad Jones, Keith E. Garrison, Jessica C. Wong, Erick H. Duan, Douglas F. Nixon, Mario A. Ostrowski DOI:...
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Granular Assembly of α-Synuclein Leading to the Accelerated Amyloid Fibril Formation with Shear Stress
Authors: Ghibom Bhak, Jung-Ho Lee, Ji-Sook Hahn, Seung R. Paik DOI: 10.1371/journal.pone.0004177 Abstract Summary Researchers discovered that α-synuclein, the protein...
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Cholesterol Pathways Affected by Small Molecules That Decrease Sterol Levels in Niemann-Pick Type C Mutant Cells
Authors: Madalina Rujoi, Nina H. Pipalia, Frederick R. Maxfield DOI: 10.1371/journal.pone.0012788 Abstract Summary Researchers identified compounds that reduce cholesterol buildup...
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Mutants of GABA Transaminase (POP2) Suppress the Severe Phenotype of succinic semialdehyde dehydrogenase ( ssadh ) Mutants in Arabidopsis
Authors: Frank Ludewig, Anke Hüser, Hillel Fromm, Linda Beauclair, Nicolas Bouché DOI: 10.1371/journal.pone.0003383 Abstract Summary Researchers found that blocking a...
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