Sunday, January 18, 2026

Presence of Circulating Anti-Myosin Antibodies in Endomyocardial Fibrosis

Authors: Ana Olga Mocumbi, Najma Latif, Magdi H. Yacoub

DOI: 10.1371/journal.pntd.0000661

Abstract Summary

Study reveals over half of endomyocardial fibrosis (EMF) patients have antibodies against heart muscle proteins, suggesting an autoimmune component to this poorly understood tropical heart disease. Researchers found IgG antibodies targeting specific myocardial proteins in 54% of EMF patients versus 10% of controls, with antibody levels correlating to disease severity. These findings could lead to better diagnosis and identify patients who might benefit from immunosuppressive treatment.

Why Brain? 🧠

Study finds anti-myosin antibodies in 54% of endomyocardial fibrosis patients versus 10% of controls, suggesting autoimmune mechanism and potential for immunosuppressive treatment in this tropical heart disease.

License: CC BY.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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