Authors: Paola Secchiero, Federica Corallini, Claudio Ceconi, Giovanni Parrinello, Stefano Volpato, Roberto Ferrari, Giorgio Zauli
DOI: 10.1371/journal.pone.0004442
Abstract Summary
Low levels of TRAIL protein in heart attack patients predict worse outcomes. This study found TRAIL levels drop sharply during acute myocardial infarction and take 6-12 months to normalize. Patients with persistently low TRAIL at discharge faced higher risks of cardiac death and heart failure, independent of traditional risk factors—suggesting TRAIL could serve as a novel prognostic biomarker.
Why Brain? đź§
Low TRAIL levels after heart attack predict higher risk of death and heart failure within 12 months, suggesting TRAIL could be a novel independent prognostic marker for cardiovascular outcomes.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
