Authors: Hesse K, Khanji MY, Chahal CAA, Chadalavada S, Fung K, Vargas JD, Paiva J, Petersen SE, Aung N.
DOI: 10.1016/j.jocmr.2025.101976
Abstract Summary
Cardiac strain heterogeneity markers (CoV) outperform traditional global strain measurements in predicting heart failure, arrhythmia, and death, especially in high-risk patients. Analyzing 60,746 UK Biobank participants, researchers found circumferential and radial strain variation coefficients detected early pathological changes better than conventional metrics, particularly when ejection fraction was preserved.
Why Brain? ๐ง
CMR strain heterogeneity metrics (CoV) outperform global strain in predicting heart failure, arrhythmia, and death, especially in high-risk patients, offering a powerful new clinical prognostic tool.
Study Limitations:
Large community-based cohort with relatively low event rates and short median follow-up of 5.1 years
Observational study design
UK Biobank participants may not be representative of general population
License: cc by.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
