Authors: Guillaume Paré, Paul M. Ridker, Lynda Rose, Maja Barbalic, Josée Dupuis, Abbas Dehghan, Joshua C. Bis, Emelia J. Benjamin, Dov Shiffman, Alexander N. Parker, Daniel I. Chasman
DOI: 10.1371/journal.pgen.1001374
Abstract Summary
A genome-wide study of over 22,000 women identified four new genetic variants linked to soluble ICAM-1, an inflammatory marker associated with heart attack, diabetes, and stroke. The discoveries include genes involved in inflammation pathways and fatty liver disease, offering new insights into how genetics regulate endothelial function and cardiovascular health.
Why Brain? 🧠
Study identifies four new genetic variants linked to soluble ICAM-1 levels, an inflammatory marker associated with heart attack, diabetes, and stroke, revealing potential targets for understanding vascular disease.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
