Authors: Daniel Dumitrescu, Ronald J. Oudiz, George Karpouzas, Arsen Hovanesyan, Amali Jayasinghe, James E. Hansen, Stephan Rosenkranz, Karlman Wasserman
DOI: 10.1371/journal.pone.0014293
Abstract Summary
Cardiopulmonary exercise testing (CPET) can detect early pulmonary vascular disease in systemic sclerosis patients before symptoms appear. In a study of 30 SSc patients without suspected lung problems, over half showed abnormal gas exchange patterns—11 had pulmonary vasculopathy and 5 had heart dysfunction. CPET successfully distinguished between these conditions, potentially enabling earlier intervention.
Why Brain? 🧠
Non-invasive cardiopulmonary exercise testing can detect early pulmonary vascular disease in systemic sclerosis patients before they develop life-threatening pulmonary hypertension, enabling earlier intervention.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
