Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth
Authors: Anita B. Hjelmeland, Qiulian Wu, Sarah Wickman, Christine Eyler, John Heddleston, Qing Shi, Justin D. Lathia, Jennifer MacSwords, Jeongwu...
Wednesday, January 21, 2026
Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy
Authors: Maria Xilouri, Tereza Vogiatzi, Kostas Vekrellis, David Park, Leonidas Stefanis DOI: 10.1371/journal.pone.0005515 Abstract Summary Mutant α-synuclein in Parkinson’s disease...
Ginseng for Health Care: A Systematic Review of Randomized Controlled Trials in Korean Literature
Authors: Jiae Choi, Tae-Hun Kim, Tae-Young Choi, Myeong Soo Lee DOI: 10.1371/journal.pone.0059978 Abstract Summary Korean medical databases reveal 30 trials...
Chronic Losartan Administration Reduces Mortality and Preserves Cardiac but Not Skeletal Muscle Function in Dystrophic Mice
Authors: Lawrence T. Bish, Mark Yarchoan, Meg M. Sleeper, Jeffrey A. Gazzara, Kevin J. Morine, Pedro Acosta, Elisabeth R. Barton,...
TRPV 1 in Brain Is Involved in Acetaminophen-Induced Antinociception
Authors: Christophe Mallet, David A. Barrière, Anna Ermund, Bo A. G. Jönsson, Alain Eschalier, Peter M. Zygmunt, Edward D. Högestätt...
Residual Antimalarials in Malaria Patients from Tanzania – Implications on Drug Efficacy Assessment and Spread of Parasite Resistance
Authors: Eva Maria Hodel, Abdunoor Mulokozi Kabanywanyi, Aggrey Malila, Boris Zanolari, Thomas Mercier, Hans-Peter Beck, Thierry Buclin, Piero Olliaro, Laurent...
Stereoselective Regulations of P-Glycoprotein by Ginsenoside Rh2 Epimers and the Potential Mechanisms From the View of Pharmacokinetics
Authors: Jingwei Zhang, Fang Zhou, Fang Niu, Meng Lu, Xiaolan Wu, Jianguo Sun, Guangji Wang DOI: 10.1371/journal.pone.0035768 Abstract Summary Researchers...
Effect of Anti-Obesity Drug on Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Yu-Hao Zhou, Xiu-Qiang Ma, Cheng Wu, Jian Lu, Shan-Shan Zhang, Jia Guo, Shun-Quan Wu, Xiao-Fei Ye, Jin-Fang Xu, Jia...
CRE/CREB-Driven Up-Regulation of Gene Expression by Chronic Social Stress in CRE-Luciferase Transgenic Mice: Reversal by Antidepressant Treatment
Authors: Ulrike Böer, Tahseen Alejel, Stephan Beimesche, Irmgard Cierny, Doris Krause, Willhart Knepel, Gabriele Flügge DOI: 10.1371/journal.pone.0000431 Abstract Summary Researchers...
Transient Responses to NOTCH and TLX1/HOX11 Inhibition in T-Cell Acute Lymphoblastic Leukemia/Lymphoma
Authors: Lesley A. Rakowski, Erica A. Lehotzky, Mark Y. Chiang DOI: 10.1371/journal.pone.0016761 Abstract Summary Researchers developed a mouse model showing...