Renal Artery Stenosis Predicts Coronary Artery Disease in Patients with Hypertension
Authors: Thiago A. Macedo, Rodrigo P. Pedrosa, Valeria Costa-Hong, Luiz J. Kajita, Gustavo R. Morais, Jose J. G. De Lima,...
Saturday, December 6, 2025
PIP5KIβ Selectively Modulates Apical Endocytosis in Polarized Renal Epithelial Cells
Authors: Christina M. Szalinski, Christopher J. Guerriero, Wily G. Ruiz, Brianne E. Docter, Youssef Rbaibi, Núria M. Pastor-Soler, Gerard Apodaca,...
PINCH1 Is Transcriptional Regulator in Podocytes That Interacts with WT1 and Represses Podocalyxin Expression
Authors: Dan Wang, Yingjian Li, Chuanyue Wu, Youhua Liu DOI: 10.1371/journal.pone.0017048 Abstract Summary PINCH1, a protein involved in cell adhesion,...
Mechanism-Based Urinary Biomarkers to Identify the Potential for Aminoglycoside-Induced Nephrotoxicity in Premature Neonates: A Proof-of-Concept Study
Authors: Stephen J. McWilliam, Daniel J. Antoine, Venkata Sabbisetti, Mark A. Turner, Tracey Farragher, Joseph V. Bonventre, B. Kevin Park,...
Chronic Obstructive Pulmonary Disease: A Growing but Neglected Global Epidemic
Authors: Peter J Barnes DOI: 10.1371/journal.pmed.0040112 Abstract Summary COPD represents a growing global health crisis that remains severely underrecognized. Despite...
Glass Shape Influences Consumption Rate for Alcoholic Beverages
Authors: Angela S. Attwood, Nicholas E. Scott-Samuel, George Stothart, Marcus R. Munafò DOI: 10.1371/journal.pone.0043007 Abstract Summary Glass shape affects drinking...
Exercise Training Improves Exercise Capacity and Quality of Life in Patients with Inoperable or Residual Chronic Thromboembolic Pulmonary Hypertension
Authors: Christian Nagel, Felix Prange, Stefan Guth, Jochen Herb, Nicola Ehlken, Christine Fischer, Frank Reichenberger, Stephan Rosenkranz, Hans-Juergen Seyfarth, Eckhard...
A Fragile Balance: Perturbation of GABA Mediated Circuit in Prefrontal Cortex Generates High Intraindividual Performance Variability
Authors: Pierre Pouget, Nicolas Wattiez, Sophie Rivaud-Péchoux, Bertrand Gaymard DOI: 10.1371/journal.pone.0005208 Abstract Summary Researchers found that disrupting the balance of...
Calcineurin Inhibition at the Clinical Phase of Prion Disease Reduces Neurodegeneration, Improves Behavioral Alterations and Increases Animal Survival
Authors: Abhisek Mukherjee, Diego Morales-Scheihing, Dennisse Gonzalez-Romero, Kristi Green, Giulio Taglialatela, Claudio Soto DOI: 10.1371/journal.ppat.1001138 Abstract Summary Researchers found that...
Alzheimer’s Disease Amyloid-β Links Lens and Brain Pathology in Down Syndrome
Authors: Juliet A. Moncaster, Roberto Pineda, Robert D. Moir, Suqian Lu, Mark A. Burton, Joy G. Ghosh, Maria Ericsson, Stephanie...