Wednesday, February 4, 2026

Initial high-dose β-blockers toleration with reduced ejection fraction heart failure of hospitalized hypertensive patients.

Authors: Li X, Yang X, Zhou Y, Wang S, Chen X.

DOI: 10.3389/fcvm.2025.1672940

Abstract Summary

New research suggests hypertensive patients with heart failure may safely start β-blockers at higher initial doses than current guidelines recommend. A study of 307 patients found no increased risk of adverse effects like bradycardia or hypotension with high-dose initiation, challenging the standard “start low, go slow” approach.

Why Brain? 🧠

Study shows hypertensive heart failure patients safely tolerate higher initial β-blocker doses than current guidelines recommend, potentially allowing faster optimization of this cornerstone therapy.

License: cc by.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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