Wednesday, February 4, 2026

Systemic angiogenic protein changes following propranolol therapy in infantile hemangioma: a multi-target perspective.

Authors: Liang L, Zhang Y, Ma Y, Liu J, Du W, Ma Q.

DOI: 10.3389/fphar.2025.1706048

Abstract Summary

Propranolol, the first-line treatment for infantile hemangiomas, works by rebalancing disrupted angiogenic proteins. Researchers found 26 proteins were abnormally low in untreated patients; after 3 months of therapy, 6 key proteins normalized, affecting pathways controlling blood vessel growth and cell proliferation. These findings reveal propranolol’s mechanism and identify potential biomarkers for monitoring treatment success.

Why Brain? 🧠

Propranolol therapy for infantile hemangiomas restores balance to dysregulated angiogenic proteins, offering new insights into treatment mechanisms and potential biomarkers for monitoring response.

License: CC BY.


The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.

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