Authors: Wang J, Li R, Fu X, Huo S, Wang L, Shao F, Gu Y.
DOI: 10.3389/fphar.2025.1686323
Abstract Summary
Researchers developed a novel nanozyme therapy for acute kidney injury (AKI) by combining catalase with manganese sulfide. The CAT@MnS nanozyme targets kidneys, simultaneously neutralizes harmful reactive oxygen species, and reduces inflammation—two key drivers of AKI. Testing in mouse models showed significant kidney protection and damage reduction, offering a promising new treatment approach for this serious condition lacking effective therapies.
Why Brain? 🧠
Novel nanozyme combining catalase with manganese sulfide effectively targets kidneys to reduce oxidative stress and inflammation in acute kidney injury models, offering a promising new therapeutic approach.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
