Authors: Yang Y, Shahinozzaman M, Shin H, Bupp S, Sourbier C.
DOI: 10.3389/fendo.2025.1601119
Abstract Summary
From animal extracts to cutting-edge biosimilars, insulin has evolved dramatically since the 1920s. Today, over 50 FDA-approved insulin products offer tailored diabetes treatment through recombinant DNA technology and innovative formulations. Recent advances include ultra-rapid formulations and combination therapies with diverse time-action profiles, making diabetes management safer, more effective, and personalized.
Why Brain? 🧠
Review traces insulin’s evolution from animal sources to modern analogs, explaining how structural and formulation changes created diverse products with varied action profiles, improving diabetes management.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
