The association between coagulation function and prognosis in patients with sepsis: a meta-analysis of predictive performance introduction.

Authors: Li C, Huang W, Han X, Li H, Qin X.

DOI: 10.3389/fmed.2025.1706082

Abstract Summary

Meta-analysis of 1,954 sepsis patients reveals fibrinogen levels inversely correlate with mortality risk, while INR shows moderate predictive value for outcomes. Though APTT and PT demonstrated reasonable diagnostic accuracy, high variability across studies limits their reliability as prognostic tools. Findings suggest specific coagulation markers could enhance sepsis risk assessment.

Why Brain? 🧠

Meta-analysis finds fibrinogen levels inversely correlate with sepsis mortality, while INR shows moderate predictive value, suggesting coagulation markers may help assess patient prognosis.

License: CC BY.

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