Development of a clinical diagnostic model for atypical endometrial hyperplasia and endometrial carcinoma in women aged 40-60 years based on refined abnormal uterine bleeding patterns.

Authors: Huang S, Hu X, Hu L, Du T, Zhao Y, Xiao J.

DOI: 10.3389/fonc.2025.1684604

Abstract Summary

Researchers developed a validated nomogram to predict risk of atypical endometrial hyperplasia and endometrial cancer in women aged 40-60 with abnormal uterine bleeding. The model incorporates seven clinical factors including age, cancer family history, and bleeding patterns, achieving strong predictive accuracy (AUC 0.814). This user-friendly tool enables early risk stratification and personalized diagnostic approaches, particularly valuable in resource-limited settings.

Why Brain? 🧠

New nomogram predicts endometrial cancer risk in women 40-60 with abnormal bleeding using seven clinical factors, achieving 81% accuracy to guide early detection and personalized care in resource-limited settings.

License: CC BY.

The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.