Authors: Lin H, Yang C, Zhu J, Yang C, Xu Z, Wu Z, Wang X, Wang W.
DOI: 10.3389/fonc.2025.1651271
Abstract Summary
A 27-year-old man developed three separate bone tumors over 10 years—a rare case of metachronous multicentric giant cell tumor. Lesions appeared sequentially in his right femur and tibia. Treatment combined mega-prosthesis revision with denosumab therapy and curettage, highlighting the need for long-term monitoring and multimodal approaches in managing this exceptionally rare condition.
Why Brain? 🧠
Rare case shows sequential bone tumors over 10 years successfully managed with denosumab therapy and prosthesis revision, highlighting effective treatment strategy for multicentric giant cell tumors.
License: CC BY.
The image is AI-generated for illustrative purposes only. Courtesy of Midjourney.
